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Degluco Tablet 500mg (Metformin) x100

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Degluco Tablet is used to manage type 2 diabetes mellitus, either as monotherapy or in combination with other antidiabetic medications.

16,000.00

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Availability: In Stock
SKU:DULC7673

Degluco Tablet 500mg contains Metformin hydrochloride as its active ingredient. This oral antidiabetic medication helps control blood sugar levels in people with type 2 diabetes by improving insulin sensitivity and reducing glucose production by the liver.

Uses

Degluco Tablet is primarily used to manage type 2 diabetes mellitus, either as monotherapy or in combination with other antidiabetic medications. It helps control blood glucose levels when diet and exercise alone aren’t sufficient. Occasionally, it may be prescribed for polycystic ovary syndrome (PCOS) or insulin resistance conditions.

Benefits

  • Effectively lowers blood glucose levels
  • Does not cause hypoglycemia when used alone
  • May support modest weight loss
  • Improves insulin sensitivity in muscles
  • Reduces liver glucose production
  • Lowers risk of diabetes-related complications
  • Does not stimulate insulin secretion
  • Cost-effective diabetes management
  • May reduce cardiovascular risk in diabetes patients

How It Works

Metformin in Degluco Tablet works by reducing glucose production in the liver, decreasing intestinal absorption of glucose, and improving insulin sensitivity in muscle and fat cells. This helps lower both fasting and post-meal blood glucose levels without stimulating insulin production, making it less likely to cause hypoglycemia.

Dosage

Patient Type Starting Dosage Maximum Daily Dosage
Adults 500mg 1-2× daily 2000mg daily
Elderly 500mg once daily 1500mg daily

Take with meals to minimize gastrointestinal side effects. Dosage should be gradually increased based on effectiveness and tolerance.

Duration of Action

Degluco begins working within hours of administration. Blood glucose-lowering effects typically appear within 48 hours, though maximum benefits may take 1-2 weeks to develop. With consistent use, Degluco provides steady blood glucose control with effects lasting approximately 12 hours per dose.

Side Effects

Common side effects include gastrointestinal disturbances such as nausea, diarrhea, abdominal discomfort, and metallic taste. These typically improve over time. Rarely, Degluco may cause vitamin B12 deficiency with long-term use. Lactic acidosis is a very rare but serious side effect requiring immediate medical attention.

Warning

Degluco should be temporarily discontinued before radiological studies involving iodinated contrast or surgical procedures. Alcohol may increase the risk of lactic acidosis and hypoglycemia. Seek immediate medical attention for severe nausea, vomiting, stomach pain, decreased appetite, dizziness, muscle pain, or difficulty breathing, which may indicate lactic acidosis.

Pregnancy and Breastfeeding

Insulin is generally preferred for managing diabetes during pregnancy rather than Degluco. Consult your healthcare provider if you become pregnant while taking this medication. Metformin passes into breast milk in small amounts. Discuss with your doctor before breastfeeding while taking Degluco.

Interaction

  • May interact with cimetidine, increasing metformin levels
  • Possible reduced effect when taken with corticosteroids
  • Increased hypoglycemia risk with alcohol consumption
  • May affect or be affected by certain antihypertensives
  • Potential interaction with iodinated contrast media
  • Could interact with thyroid medications if taken simultaneously

Precaution

Kidney function should be monitored regularly while taking Degluco. Use with caution in elderly patients and those with liver impairment. Temporarily discontinue during periods of tissue hypoxia. Monitor for vitamin B12 deficiency with long-term use. May need to be suspended during severe illness, surgery, or significant medical procedures.

Important Information

Degluco Tablet is an aid to, not a substitute for, proper diet and exercise. Regular blood glucose monitoring is essential. Never stop taking without consulting your healthcare provider. Carry identification indicating you have diabetes. This medication works best as part of a comprehensive diabetes management plan that includes proper diet, regular exercise, and lifestyle modifications.

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Category Dosage Instructions
Adults (Type 2 Diabetes) Start with 500mg once or twice daily with meals. Increase gradually by 500mg weekly based on blood glucose levels. Max: 2000–2550mg/day in divided doses.
Elderly Patients Start at lower dose (e.g. 500mg once daily). Monitor kidney function regularly.
Children (10 years and above) Start with 500mg once daily. Can be increased gradually. Max: 2000mg/day in divided doses.
Renal Impairment Not recommended if eGFR < 30 ml/min/1.73 m². Use with caution if eGFR is between 30–45 ml/min.

How to Use

  • Take with meals to reduce the risk of gastrointestinal side effects.

  • Swallow tablet whole with a glass of water—do not crush or chew.

  • Try to take it at the same time each day for best results.


Important Information

  • Regular monitoring of blood sugar and kidney function is advised.

  • Avoid alcohol, which increases the risk of lactic acidosis.

  • Common side effects include nausea, diarrhea, and abdominal discomfort—usually improve with continued use.

  • Not for use in Type 1 diabetes or during episodes of diabetic ketoacidosis.

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